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Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells (By similarity). .
Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118) Lifr
Rat,Mouse
WB
WB 1:1000-1:2000
123kD
Lifr
P42703,O70535
Rabbit
Polyclonal
Rabbit IgG
Product Information
| Description | LIFR rabbit polyclonal |
| Protein full name | Leukemia inhibitory factor receptor |
| Synonyms | LIF receptor, LIF-R, D-factor/LIF receptor, CD118, Lifr, SJS2, STWS, LIF-R |
| Immunogen | Recombinantproteincorrespondingto Mouse LIFR |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 123 kDa |
| Observed MW. | 190 kDa |
| Uniprot ID | P42703, O70535 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse,Rat | 1:500-1:1000 | heart, liver, kidney, placenta |
Background
LIFR, also known as CD118, is a subunit of a receptor for leukemia inhibitory factor (LIF). LIF is a pleiotropic cytokine of the interleukin-6 family which affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR is the low-affinity binding chain that, together with the high-affinity converter subunit gp130, forms a high-affinity receptor complex that mediates the action of LIF. The high-affinity complex also binds a related cytokine, oncostatin M. LIFR has also been identified as a breast cancer metastasis suppressor that functions through the HIPPO-YAP pathway.
Images
 | Western blot analysis of LIFR (T611476M) at dilution of 1: 1000 Lane 1: Mouse heart tissue lysate Lane 2: Mouse liver tissue lysate Lane 3: Mouse kidney tissue lysate Lane 4: Mouse placenta tissue lysate Lane 5: Rat liver tissue lysate Lane 6: Rat placenta tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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