Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.
Immunoglobulin-binding protein 1 (Alpha4 phosphoprotein) (CD79a-binding protein 1) (Lymphocyte signal transduction molecule alpha 4) (Protein phosphatase 2/4/6 regulatory subunit) (p52) Igbp1 Pc52
Human,Mouse
WB
WB 1:1000-1:2000
39kD
Igbp1 Pc52
Q61249
Rabbit
Polyclonal
Rabbit IgG
B-cell activation
Product Information
| Description | IGBP1 rabbit polyclonal |
| Protein full name | Immunoglobulin-binding protein 1 |
| Synonyms | Alpha4 phosphoprotein, CD79a-binding protein 1, Lymphocyte signal transduction molecule alpha 4, Protein phosphatase 2/4/6 regulatory subunit, p52, Igbp1, Pc52 |
| Immunogen | Recombinantproteincorrespondingto Mouse IGBP1 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 39 kDa |
| Observed MW. | 39 kDa |
| Uniprot ID | Q61249 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse | 1:500-1:1000 | spleen, thymus |
Background
Immunoglobulin-binding protein 1 (IGBP1), also known as ALPHA-4, was originally identified as a signal transduction molecule coprecipitating with MB1 (CD79a) protein of the B-cell antigen receptor (BCR) complex. IGBP1 has been characterized as an essential regulator of the catalytic activity of protein phosphatase 2A (PP2A), which is a ubiquitous phosphatase with broad substrate specificity and diverse cellular functions.
Images
![]() | Western blot analysis of IGBP1 (T611561M) at dilution of 1: 1000 Lane 1: K562 cell lysate Lane 2: Mouse spleen tissue lysate Lane 3: Mouse thymus tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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应聘职位:hr@ab-mart.com
订购专线:4006-123-828
销售电话:13916964679(微信同号)
技术支持:15618194176(微信同号)
华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:
陆经理:手机13122837132(微信同号)
北方及西南经销商负责:
张经理:手机13122150513(微信同号)

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