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Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Plays a role in the mitochondrial apoptotic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. .
Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7) BAK1 BAK BCL2L7 CDN1
Human,Rat,Mouse
WB
WB 1:1000-1:2000
24kD
BAK1 BAK BCL2L7 CDN1
Q16611,O08734
Rabbit
Polyclonal
Rabbit IgG
Apoptosis
Product Information
Description | Bakrabbit polyclonal |
Protein full name | Bcl-2 homologous antagonist/killer |
Synonyms | BAK,BAK1,BCL2L7,CDN1,Apoptosis Regulator Bak |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse BAK |
Isotype | IgG |
Predicted MW. | 25kDa |
Observed MW. | 25kDa |
Purity | Affinity purification |
Uniprot ID | Q16611,O08734 |
Applications
applications | species | dilution | Positive tissue |
WB | Human,Mouse,Rat | 1:500-1:1000 | heart,kidney |
Background
In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis .
Images
| Western blot analysis of Bak (T61324M) at dilution of 1:1000. Lane 1:MCF7 cell lysate Lane 2:Raw264.7 cell lysate Lane 3:Mouse heart tissue lysate Lane 4:Mouse skeletal muscle tissue lysate Lane 5:Mouse kidney tissue lysate Lane 6:Rat heart tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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