Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif . Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression (By similarity). Involved in skeletal myoblast differentiation by promoting gene expression of CALD1 . .
Transcription factor SOX-4 SOX4
Human,Rat,Mouse
WB
WB 1:1000-1:2000
48kD
SOX4
Q06945,Q06831
Rabbit
Polyclonal
Rabbit IgG
Differentiation #anatomical structure morphogenesis,
Product Information
Description | SOX4 rabbit polyclonal |
Protein full name | Transcription factor SOX-4 |
Synonyms | SOX4, EVI16, SRY-box 4, Ecotropic viral integration site 16, SRY box containing gene 4, SRY related HMG box gene 4 |
Immunogen | KLH conjugated Synthetic peptide corresponding to MouseSOX4 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Nucleus |
Predicted MW. | 45 kDa |
Observed MW. | 45 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human,Mouse,Rat | 1:500-1:1000 | testis, kidney, brain |
Background
Transcription factor SOX-4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may also function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development.
Images
![]() | Western blot analysis of SOX4 (T61699) at dilution of 1: 1000 Lane 1: Jurkat cell lysate Lane 2: SH-SY5Y cell lysate Lane 3: 293T cell lysate Lane 4: Mouse kidney tissue lysate Lane 5: Mouse brain tissue lysate Lane 6: Mouse testis tissue lysate Lane 7: Rat kidney tissue lysate Lane 8: Rat brain tissue lysate Lane 9: Rat testis tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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应聘职位:hr@ab-mart.com
订购专线:4006-123-828
销售电话:13916964679(微信同号)
技术支持:15618194176(微信同号)
华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:
陆经理:手机13122837132(微信同号)
北方及西南经销商负责:
张经理:手机13122150513(微信同号)

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