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Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
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Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues (By similarity). Regulates the cellular cytoskeleton by enhancing actin stress fiber formation via phosphorylation of cofilin and by preventing microtubule breakdown via inhibition of TAOK1/MARKK kinase activity (By similarity). Inhibits podocyte motility via regulation of actin cytoskeletal dynamics and phosphorylation of CFL1 (By similarity). Positively regulates integrin-mediated cell spreading, via phosphorylation of cofilin . Suppresses ciliogenesis via multiple pathways; phosphorylation of CFL1, suppression of ciliary vesicle directional trafficking to the ciliary base, and by facilitating YAP1 nuclear localization where it acts as a transcriptional corepressor of the TEAD4 target genes AURKA and PLK1 . Probably plays a central role at and after the meiotic phase of spermatogenesis (By similarity). .
Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1) TESK1
Human,Mouse
WB,IHC,IF,ICC
WB 1:1000-1:2000IHC 1:50-1:200IF 1:100-1:400ICC 1:100-1:400
68kD
TESK1
Q15569,O70146
Rabbit
Polyclonal
Rabbit IgG
Spermatogenesis #phosphorylation
Product Information
| Description | TESK1 rabbit polyclonal |
| Protein full name | Dual specificity testis-specific protein kinase 1 |
Synonyms | Tesk1, TESK1, testis-specific kinase 1, testis associated actin remodelling kinase 1 |
| Immunogen | Recombinantproteincorrespondingto Mouse TESK1 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Nucleus, Cytoplasm |
Predicted MW. | 68 kDa |
Observed MW. | 68 kDa |
| Uniprot ID |
Applications
| Applications | WB | IHC | IF |
| Species | Human, Mouse | Mouse,Rat | Mouse,Rat |
| Dilution | 1:500-1:1000 | 1:1000-1:2000 | 1:500-1:1000 |
| Positive tissue | 293T, MCF7,U87, NIH/3T3 | testis, brain | testis, brain |
Background
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Probably plays a central role at and after the meiotic phase of spermatogenesis.
Images
| Western blot analysis of TESK1 (T61930M) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mousetestisusing TESK1(T61930M)at dilution of 1:500 |
| Immunohistochemistry analysis of paraffin-embedded mouse brainusing TESK1(T61930M) at dilution of 1:500 |
| Immunohistochemistry analysis of paraffin-embedded rat brainusing TESK1(T61930M) at dilution of 1:500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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