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Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). .
Myelin basic protein (MBP) Mbp
Human,Rat,Mouse
WB,IHC,IF,ICC
WB 1:1000-1:2000IHC 1:50-1:200IF 1:100-1:400ICC 1:100-1:400
22kD
Mbp
P04370,P02688
Mouse
Monoclonal
Mouse IgG
Mercuric resistance #Detoxification #Hearing
Product Information
| Description | Myelin Basic Protein mousemonoclonal |
| Proteinfull name | Myelin Basic Protein |
| Synonyms | MBP, entrez:4155, myelin basic protein |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Myelin Basic Protein |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 27KDa |
| Observed MW. | 18.5/22KDa |
| Subcellular location | Myelin membrane,Cytoplasmic side of myelin |
| Uniprot ID | P04370, P02688 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse,Rat | 1:2000-1:4000 | brain, cerebral cortex, hippocampus |
| IHC | Mouse,Rat | 1:500-1:1000 | cerebral cortex |
| IF | Mouse,Rat | 1:250-1:500 | cerebral cortex |
Background
The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells.
Images
 | Western blot analysis of Myelin Basic Protein (T62226M) at dilution of 1:3000. Lane 1:Humanbrain tissue lysate Lane 2:Mouse braintissue lysate Lane 3:Mouse cerebralcortextissue lysate Lane 4:Mouse hippocampus tissue lysate Lane 5:Rat brain tissue lysate Lane 6:Rat cerebral cortex tissue lysate Lane 7:Rat hippocampus tissue lysate |
 | Immunohistochemistry analysis of paraffin-embedded mouse cerebralcortexusing Myelin Basic Protein (T62226M) at dilution of 1:3000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
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程经理：手机18616261485（微信同号）
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徐经理：手机15618191473（微信同号）
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