Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2.
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT) DNMT1 AIM CXXC9 DNMT
Human,Mouse,Rat
Monkey,Dog,Pig,Cat,Horse,Sheep,Bovine,Hamster,Guinea Pig,Chicken,Xenopus,Zebrafish
WB,IHC,IF,ICC
WB 1:500-1:2000IHC 1:50-1:200IF 1:50-1:200ICC 1:50-1:200
183kDa
DNMT1 AIM CXXC9 DNMT
p26358
A synthesized peptide derived from human Dnmt1
Rabbit
Monoclonal
Rabbit IgG
Dnmt1 Antibody detects endogenous levels of total Dnmt1
Nucleus localization
Affinity-chromatography
PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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