Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway.
Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production.
Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect.
Enhances Notch signaling pathway in a non-cell-autonomous manner via direct interaction with NOTCH2.
Also promotes Notch signaling pathway in a cell-autonomous manner through inhibition of cis DLL1-NOTCH2 interactions, which promotes neuronal differentiation.
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein) NOTCH2NLA N2N NOTCH2NL
Human
WB,IHC
WB 1:2000-5000IHC 1:25-100
25/26/27kDa
388677
q7z3s9
Recombinant protein of human NOTCH2NL
1-237aa
Rabbit
Polyclonal
IgG
Cytoplasm
Differentiation #Notch signaling pathway
Affinity purification
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Store at -20℃. Avoid freeze / thaw cycles.
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