Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).
High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4) HMGB3 HMG2A HMG4
Human, Mouse
WB,IF,ICC,ELISA
WB 1:500-1:2000IF 1:50-1:500ICC 1:50-1:500ELISA 1:2000
23kD; 23kDa(Calculated).
HMGB3 HMG2A HMG4
o15347
Rabbit
Polyclonal
Rabbit IgG
HMGB3 Antibody detects endogenous levels of total HMGB3.
DNA recombination #Innate immunity #DNA recombination
PBS,pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Store at -20 °C. Stable for 12 months from date of receipt.
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