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Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Signal transducing adapter molecule 1 is a protein that in humans is encoded by the STAM gene. This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains an SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors. HGS/HRS (hepatocyte growth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein.[6] STAM1 contains multiple amino acid sites that are phosphorylated and ubiquitinated.
Signal transducing adapter molecule 1 (STAM-1) STAM STAM1
Human,Rat
IHC,IF,ICC
IHC 1:200-1:600IF 1:100-1:400ICC 1:200
Predicted band size: 59 kDa
STAM STAM1
q92783
Rabbit
Polyclonal
Rabbit IgG
signal transduction
Siha, SHSY5Y, human kidney tissue, human colon tissue, Rat testis tissue.
Immunogen affinity purified.
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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