TD9074

货号 规格 价格(¥)
TD9074S 50μl
TD9074M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

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   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-ALKBH7 Antibody

Datasheet

Background

May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate. Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death. ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage. Does not display DNA demethylase activity. Involved in fatty acid metabolism (By similarity).

Alternative Name

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 7) (Spermatogenesis cell proliferation-related protein) (Spermatogenesis-associated protein 11) ALKBH7 ABH7 SPATA11 UNQ6002/PRO34564

Reactivity

Human, Mouse, Monkey

Predicted Reactivity

Pig, Bovine, Horse, Sheep, Rabbit, Dog

Application

WB,IHC,IF,ICC

Application Image

Recommended Dilution

WB 1:500-1:2000
IHC 1:50-1:500
IF 1:50-1:500
ICC 1:50-1:500

Mol Weight

24kD; 25kDa(Calculated).

Gene Symbol

ALKBH7 ABH7 SPATA11 UNQ6002/PRO34564

Uniprot

q9bt30

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Polyclonal

Isotype

Rabbit IgG

Specificity

ALKBH7 Antibody detects endogenous levels of total ALKBH7.

Subcellular location

Research Area

DNA damage #Fatty acid metabolism

Positive control

Conjugation

Modification

Purification

Formulation

Concentration

Buffer

PBS,pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

产品介绍

Clone

Target

波长

Storage

Store at -20 °C. Stable for 12 months from date of receipt.

注意事项

Companion Products

Important

Comments

RRID

客户评价

艾比玛特医药科技(上海)有限公司
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技术支持:15618194176(微信同号)

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华北经销商负责(北京,天津,河北):
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南方经销商负责:

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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