Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2-alpha/EIF2S1) on 'Ser-52' during the unfolded protein response (UPR) and in response to low amino acid availability. Converts phosphorylated eIF-2-alpha/EIF2S1 either in a global protein synthesis inhibitor, leading to a reduced overall utilization of amino acids, or to a translation initiation activator of specific mRNAs, such as the transcriptional activator ATF4, and hence allowing ATF4-mediated reprogramming of amino acid biosynthetic gene expression to alleviate nutrient depletion. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function.
Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK) EIF2AK3 PEK PERK
Human,Mouse,Rat
WB,IHC,IF,ICC,ELISA
WB 1:500-1000IHC 1:50-100IF 1:50-200ICC 1:100-1:400ELISA 1:10000
125kDa
9451
q9nzj5
A synthetic peptide of human Phospho-PERK (Thr982)
Rabbit
Polyclonal Antibody
IgG
Cytoplasm
Angiogenesis
Affinity purification
Buffer: PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Store at -20℃. Avoid freeze / thaw cycles.
AB_3716597
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订购专线:4006-123-828
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程经理:手机18616261485(微信同号)
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徐经理:手机15618191473(微信同号)
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