13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
RNA-binding protein that is involved in various steps of RNA biogenesis and processing . Preferentially binds, via its two RNA recognition motifs RRM1 and RRM2, to GU-repeats on RNA molecules predominantly localized within long introns and in the 3''UTR of mRNAs . In turn, regulates the splicing of many non-coding and protein-coding RNAs including proteins involved in neuronal survival, as well as mRNAs that encode proteins relevant for neurodegenerative diseases . Plays a role in maintaining mitochondrial homeostasis by regulating the processing of mitochondrial transcripts . Regulates also mRNA stability by recruiting CNOT7/CAF1 deadenylase on mRNA 3''UTR leading to poly(A) tail deadenylation and thus shortening . In response to oxidative insult, associates with stalled ribosomes localized to stress granules (SGs) and contributes to cell survival . Participates also in the normal skeletal muscle formation and regeneration, forming cytoplasmic myo-granules and binding mRNAs that encode sarcomeric proteins . Plays a role in the maintenance of the circadian clock periodicity via stabilization of the CRY1 and CRY2 proteins in a FBXL3-dependent manner . Negatively regulates the expression of CDK6 . Regulates the expression of HDAC6, ATG7 and VCP in a PPIA/CYPA-dependent manner . .
TAR DNA-binding protein 43 (TDP-43),TARDBP TDP43
q13148
Mouse
Monoclonal
IgG1
Human
WB,IHC,IP
WB 1:1000IHC 1:200IP 1:100
45kD
Supplied as solution in phosphate buffered saline containing 0.09% sodium azide
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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