MU01308

货号 规格 价格(¥)
MU01308S 50ul
MU01308M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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经典一抗-RBM15B Antibody

Datasheet

Background

RNA-binding protein that acts as a key regulator of N6-methyladenosine (m6A) methylation of RNAs, thereby regulating different processes, such as alternative splicing of mRNAs and X chromosome inactivation mediated by Xist RNA. Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Plays a key role in m6A methylation, possibly by binding target RNAs and recruiting the WMM complex. Involved in random X inactivation mediated by Xist RNA: acts by binding Xist RNA and recruiting the WMM complex, which mediates m6A methylation, leading to target YTHDC1 reader on Xist RNA and promoting transcription repression activity of Xist. Functions in the regulation of alternative or illicit splicing, possibly by regulating m6A methylation. Inhibits pre-mRNA splicing. Also functions as a mRNA export factor by acting as a cofactor for the nuclear export receptor NXF1.

Alternative Name

1810017N16Rik antibody
Chromosome 3p21.1 gene sequence antibody
HUMAGCGB antibody
huOTT3 antibody
One twenty two protein 3 antibody
One-twenty two protein 3 antibody
OTT3 antibody
Putative RNA binding protein 15B antibody
Putative RNA-binding protein 15B antibody
RB15B_HUMAN antibody
RBM15B antibody
RGD1305937 antibody
RNA binding motif protein 15B antibody
RNA-binding motif protein 15B antibody

Reactivity

Human,Mouse,Rat

Application

WB

Recommended Dilution

WB 1:2000

Application Image

Mol Weight

Predicted band size: 97 kDa

Gene Symbol

RBM15B, OTT3

Uniprot

q8ndt2>swissprot: q8ndt2 human;swissprot: q6phz5 mouse;entrez gene: 315988 rat

Uniprot link

Immunogen

Immunogen Range

Source

Mouse

Clonality

Mouse monoclonal Antibody

Isotype

IgG1

Specificity

Subcellular location

Nucleus, nucleoplasm, Nucleus speckle, Nucleus envelope.

Research Area

Signal Transduction->Protein Trafficking;Epigenetics and Nuclear Signaling->DNA / RNA;Epigenetics and Nuclear Signaling->Chromatin Binding Proteins;Metabolism->lipid and Glucose metabolism

Positive control

HeLa cell lysate, 293T cell lysate, Jurkat cell lysate, RAW264.7 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

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技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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