TU21791

货号 规格 价格(¥)
TU21791S 50ul
TU21791M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

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   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Phospho-MDM2 (S166) Antibody

Datasheet

Background

This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

Alternative Name

ACTFS antibody
Double minute 2 protein antibody
E3 ubiquitin-protein ligase Mdm2 antibody
Hdm 2 antibody
Hdm2 antibody
HDMX antibody
MDM 2 antibody
MDM2 antibody
MDM2 oncogene E3 ubiquitin protein ligase antibody
Mdm2 p53 E3 ubiquitin protein ligase homolog antibody
Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa antibody
MDM2_HUMAN antibody
MDM2BP antibody
Mouse Double Minute 2 antibody
MTBP antibody
Murine Double Minute Chromosome 2 antibody
Oncoprotein Mdm2 antibody
p53 Binding Protein Mdm2 antibody
p53-binding protein Mdm2 antibody
Ubiquitin protein ligase E3 Mdm2 antibody
Ubiquitin protein ligase E3 Mdm2 antibody

Reactivity

Human,Mouse,Rat

Application

WB

Recommended Dilution

WB 1:1000

Application Image

Mol Weight

Predicted band size: 55 kDa

Gene Symbol

MDM2

Uniprot

q00987>swissprot: q00987 human;swissprot: p23804 mouse

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Recombinant Rabbit monoclonal Antibody

Isotype

IgG

Specificity

Subcellular location

Nucleus, nucleoplasm, nucleolus, cytoplasm.

Research Area

Cell Biology->Cell Cycle;Cell Biology->Cell Cycle->Cell Cycle Inhibitors->p53;Cancer->Oncoproteins/suppressors;Cancer->Cell cycle;Cancer->Cell cycle->Cell cycle inhibitors->p53 pathway;Epigenetics and Nuclear Signaling->Transcription->Other factors;Epigenetics and Nuclear Signaling->ChIP assays;Epigenetics and Nuclear Signaling->ChIP assays->ChIP antibodies;Epigenetics and Nuclear Signaling->Ubiquitin & Ubiquitin Like Modifiers;Epigenetics and Nuclear Signaling->Ubiquitin & Ubiquitin Like Modifiers->E3 Ubiquitin Ligases

Positive control

A549 cell lysate.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

艾比玛特医药科技(上海)有限公司
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应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

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