TU21793

货号 规格 价格(¥)
TU21793S 50ul
TU21793M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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经典一抗-Phospho-RSK1 p90 (T573) Antibody

Datasheet

Background

The family of ribosomal S6 kinases (Rsks), designated Rsk-1, Rsk-2 and Rsk-3, are important signaling intermediates that mediate responses to a broad range of ligand-activated receptor tyrosine kinases. It has been established that Rsk-3 is not activated by MAP kinase in vitro, unlike Rsk-1 and Rsk-2. A unique feature common to the three members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. The Rsk family amino-terminal kinase domain is phosphorylated on Ser 227 by 3-phosphoinositide-dependent protein kinase-1 (PDK1), which increases the kinase activity of Rsk. In the carboxy-terminal kinase domain, Rsk-1 and Rsk-2 are autophosphorylated on Ser 380 and Ser 386, respectively, which mediates the docking of PDK1 to Rsk in order to promote phosphorylation of substrates, such as histone H3.

Alternative Name

90 kDa ribosomal protein S6 kinase 1 antibody
dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1 antibody
dJ590P13.1 antibody
EC 2.7.11.1 antibody
HU 1 antibody
HU1 antibody
KS6A1_HUMAN antibody
MAP kinase activated protein kinase 1a antibody
MAP kinase-activated protein kinase 1a antibody
MAPK-activated protein kinase 1a antibody
MAPKAP kinase 1a antibody
MAPKAPK-1a antibody
MAPKAPK1A antibody
MGC79981 antibody
Mitogen-activated protein kinase-activated protein kinase 1A antibody
OTTHUMP00000004113 antibody
p90 RSK1 antibody
p90-RSK 1 antibody
p90rsk antibody
p90RSK1 antibody
p90S6K antibody
pp90RSK1 antibody
Ribosomal protein S6 kinase 90kD 1 antibody
Ribosomal protein S6 kinase 90kD polypeptide 1 antibody
Ribosomal protein S6 kinase 90kDa polypeptide 1 antibody
Ribosomal protein S6 kinase alpha 1 antibody
Ribosomal protein S6 kinase alpha-1 antibody
Ribosomal protein S6 kinase polypeptide 1 antibody
Ribosomal S6 kinase 1 antibody
RPS6K1 alpha antibody
rps6ka antibody
Rps6ka1 antibody
RSK 1 antibody
RSK 1 p90 antibody
RSK antibody
RSK-1 antibody
RSK1 antibody
S6K alpha 1 antibody
S6K-alpha-1 antibody

Reactivity

Human,Mouse,Rat

Application

WB

Recommended Dilution

WB 1:1000

Application Image

Mol Weight

Predicted band size: 83 kDa

Gene Symbol

S6K-alpha-1, p90-RSK 1, p90RSK1, p90S6K, MAPK-activated protein kinase 1a, MAPKAP kinase 1a, MAPKAPK-1a, RSK-1, RPS6KA1

Uniprot

q15418>swissprot: q15418 human;swissprot: p18653 mouse;swissprot: q63531 rat

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Recombinant Rabbit monoclonal Antibody

Isotype

IgG

Specificity

Subcellular location

Nucleus, Cytoplasm.

Research Area

Signal Transduction->Protein Phosphorylation;Signal Transduction->Protein Phosphorylation->Ser / Thr Kinases->MAPK Pathway;Epigenetics and Nuclear Signaling->Transcription->Other factors

Positive control

K-562 treated with 500nM PMA for 15 minutes cell lysate, HeLa treated with 200nM PMA for 4 hours cell lysate.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

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技术支持:15618194176(微信同号)

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南方经销商负责:

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

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