The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/ threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated α, β,γandδ, which may or may not be coexpressed in the same tissue types. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation. Stimulation of the T cell receptor CD3 signaling complex with an CD3 monoclonal antibody leads to a 10-40 fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory threonine residue at position 177.

Calcium/calmodulin dependent protein kinase II alpha antibody
Calcium/calmodulin dependent protein kinase II beta antibody
Calcium/calmodulin dependent protein kinase II delta antibody
Calcium/calmodulin dependent protein kinase II gamma antibody
Calcium/calmodulin-dependent protein kinase type II subunit alpha antibody
CaM kinase II alpha antibody
CaM kinase II antibody
CaM kinase II beta antibody
CaM kinase II delta antibody
CaM kinase II gamma antibody
CaM kinase II subunit alpha antibody
CaMK-II subunit alpha antibody
CAMK2 antibody
Camk2a antibody
CAMK2B antibody
CAMK2D antibody
CAMK2G antibody
CAMKA antibody
KCC2A_HUMAN antibody

Human,Mouse,Rat

WB

WB 1000

Predicted band size: 54 kDa

CAMK2A, CAMKA, KIAA0968, CAMK2B, CAM2, CAMK2, CAMKB, CAMK2D, CAMKD, CAMK2G, CAMK, CAMK-II, CAMKG

q13554>swissprot: q13554 human;swissprot: q13555 human;swissprot: q13557 human;swissprot: q9uqm7 human

Rabbit

Recombinant Rabbit monoclonal Antibody

IgG

Synapse, Postsynaptic density, Cell projection, dendritic spine, dendrite.

Cell Biology->Cell Cycle;Cancer->Cancer Metabolism;Cancer->Cancer Metabolism->Metabolic signaling pathway->Metabolism of carbohydrates;Cancer->Cancer Metabolism->Response to hypoxia;Cancer->Cell cycle;Cancer->Cell cycle->Kinases/phosphatases->Other;Signal Transduction->Protein Phosphorylation;Signal Transduction->Protein Phosphorylation->Ser / Thr Kinases->Other Kinases;Cardiovascular->Heart;Cardiovascular->Heart->Hypertrophy->Other;Cardiovascular->Heart->Apoptosis;Epigenetics and Nuclear Signaling->Cell cycle;Epigenetics and Nuclear Signaling->Cell cycle->Kinases/Phosphatases->Other;Metabolism->Cancer Metabolism;Neuroscience->Neuronal Marker;Neuroscience->Neurodevelopmental disorders: ASD;Neuroscience->Calcium Signaling

Human brain tissue lysate, mouse brain tissue lysate, rat brain tissue lysate.

Protein A affinity purified.

Liquid

1 mg/mL.

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.