TU21866

货号 规格 价格(¥)
TU21866S 50ul
TU21866M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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经典一抗-Phospho-Glucose Transporter GLUT4 (S488) Antibody

Datasheet

Background

Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene. GLUT4 is the insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). The first evidence for this distinct glucose transport protein was provided by David James in 1988. The gene that encodes GLUT4 was cloned and mapped in 1989. At the cell surface, GLUT4 permits the facilitated diffusion of circulating glucose down its concentration gradient into muscle and fat cells. Once within cells, glucose is rapidly phosphorylated by glucokinase in the liver and hexokinase in other tissues to form glucose-6-phosphate, which then enters glycolysis or is polymerized into glycogen. Glucose-6-phosphate cannot diffuse back out of cells, which also serves to maintain the concentration gradient for glucose to passively enter cells.

Alternative Name

Glucose transporter GLUT 4
Glucose transporter type 4
Glucose transporter type 4 insulin responsive
GLUT 4
GLUT-4
GLUT4
GTR4_HUMAN
Insulin responsive glucose transporter type 4
insulin-responsive
kug
SLC 2A4
SLC2A4
solute carrier family 2 (facilitated glucose transporter) member 4
Solute carrier family 2 member 4
Solute carrier family 2, facilitated glucose transporter member 4

Reactivity

Mouse,Human,Rat

Application

WB

Recommended Dilution

WB 1:1000

Application Image

Mol Weight

Predicted band size: 55 kDa

Gene Symbol

SLC2A4, GLUT4, GLUT-4

Uniprot

p14672>swissprot: p14672 human;swissprot: p14142 mouse;swissprot: p19357 rat

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Recombinant Rabbit monoclonal Antibody

Isotype

IgG

Specificity

Subcellular location

Cell membrane, Endomembrane system, Cytoplasm, perinuclear region.

Research Area

Stem cells->Mesenchymal Stem Cells;Stem cells->Mesenchymal Stem Cells->Adipogenesis;Cancer->Cancer Metabolism;Cancer->Cancer Metabolism->Metabolic signaling pathway->Metabolism of carbohydrates;Signal Transduction->Metabolism;Signal Transduction->Metabolism->Energy Metabolism;Cardiovascular->Heart;Cardiovascular->Heart->Cardiac metabolism;Metabolism->Cancer Metabolism;Metabolism->Diabetes

Positive control

Mouse heart tissue lysates (no heat).

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

艾比玛特医药科技(上海)有限公司
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应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

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