TU21980

货号 规格 价格(¥)
TU21980S 50ul
TU21980M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Phospho-IRE1 (S724) Antibody

Datasheet

Background

The serine/threonine-protein kinase/endoribonuclease inositol-requiring enzyme 1 α (IRE1α) is an enzyme that in humans is encoded by the ERN1 gene. The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals (mainly the unfolded protein response). Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Name

Endoplasmic reticulum (ER) to nucleus signalling 1 antibody
Endoplasmic reticulum to nucleus signaling 1 antibody
Endoplasmic reticulum-to-nucleus signaling 1 antibody
Endoribonuclease antibody
ER to nucleus signaling 1 antibody
ERN 1 antibody
Ern1 antibody
ERN1_HUMAN antibody
hIRE 1p antibody
hIRE1p antibody
Inositol requiring 1 antibody
Inositol requiring 1, S. cerevisiae, homolog of antibody
Inositol requiring enzyme 1, S. cerevisiae, homolog of antibody
Inositol requiring protein 1 antibody
inositol-requiring enzyme 1 antibody
Inositol-requiring protein 1 antibody
IRE 1 antibody
IRE 1a antibody
IRE 1P antibody
Ire1 alpha antibody
Ire1-alpha antibody
IRE1a antibody
Ire1alpha antibody
IRE1P antibody
MGC163277 antibody
MGC163279 antibody
Protein kinase/endoribonuclease antibody
RGD1559716 antibody
Serine/threonine protein kinase/endoribonuclease IRE1 antibody

Reactivity

Human,Mouse

Application

WB,IHC,IF,ICC,FC

Recommended Dilution

WB 1:1000
IHC 1:500
IF 1:100-1:400
ICC 1:500
FC 1:1000

Application Image

Mol Weight

Predicted band size: 110 kDa

Gene Symbol

ERN1, IRE1

Uniprot

o75460>swissprot: o75460 human;swissprot: q9eqy0 mouse

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Recombinant Rabbit monoclonal Antibody

Isotype

IgG

Specificity

Subcellular location

Endoplasmic reticulum membrane; nucleus.

Research Area

Positive control

HeLa starved for 3 hours then treated with 100nM Calyculin A for 30 minutes cell lysate, Jurkat treated with 100nM Calyculin A for 30 minutes cell lysate, Jurkat cells treated with 100nM Calyculin A for 30 minutes, human pancreas tissue, HeLa cells treated with 100nM Calyculin A for 30 minutes.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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