TU21987

货号 规格 价格(¥)
TU21987S 50ul
TU21987M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

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   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Phospho-CDK1 (T161) Antibody

Datasheet

Background

Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine protein kinase, and is a key player in cell cycle regulation. It has been highly studied in the budding yeast S. cerevisiae, and the fission yeast S. pombe, where it is encoded by genes cdc28 and cdc2, respectively. With its cyclin partners, Cdk1 forms complexes that phosphorylate a variety of target substrates (over 75 have been identified in budding yeast); phosphorylation of these proteins leads to cell cycle progression.

Alternative Name

Cdc 2 antibody
Cdc2 antibody
CDC28A antibody
CDK 1 antibody
CDK1 antibody
CDK1_HUMAN antibody
CDKN1 antibody
CELL CYCLE CONTROLLER CDC2 antibody
Cell division control protein 2 antibody
Cell division control protein 2 homolog antibody
Cell division cycle 2 G1 to S and G2 to M antibody
Cell division protein kinase 1 antibody
Cell Divsion Cycle 2 Protein antibody
Cyclin Dependent Kinase 1 antibody
Cyclin-dependent kinase 1 antibody
DKFZp686L20222 antibody
MGC111195 antibody
p34 Cdk1 antibody
p34 protein kinase antibody
P34CDC2 antibody

Reactivity

Human,Mouse,Rat

Application

WB,IHC,IF,ICC,FC

Recommended Dilution

WB 1:2000
IHC 1:200
IF 1:100-1:400
ICC 1:2500
FC 1:100

Application Image

Mol Weight

Predicted band size: 34 kDa

Gene Symbol

CDK1, CDC2, CDC28A, CDKN1, P34CDC2

Uniprot

p06493>swissprot: p06493 human;swissprot: p11440 mouse;swissprot: p39951 rat

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Recombinant Rabbit monoclonal Antibody

Isotype

IgG

Specificity

Subcellular location

Nucleus, Mitochondrion, Cytoplasm, cytoskeleton, microtubule organizing center, spindle.

Research Area

Cell Biology->Cell Cycle;Epigenetics and Nuclear Signaling->Cell cycle;Epigenetics and Nuclear Signaling->Cell cycle->Kinases/Phosphatases->Cdks;Signal Transduction->Cell Cycle and Checkpoint Controls;Neuroscience->Neurodegenerative disorders

Positive control

HeLa cell lysate, HeLa treated with 100nM Calyculin A for 30 minutes cell lysate, Jurkat cell lysate, Jurkat treated with 100nM Calyculin A for 30 minutes cell lysate, NIH/3T3 cell lysate, NIH/3T3 treated with 100nM Calyculin A for 30 minutes cell lysate, PC-12 cell lysate, PC-12 treated with UV for 1 hour cell lysate, human cervix cancer tissue, Jurkat cells treated with 100nM Calyculin A for 30 minutes, HeLa cells treated with 100nM Calyculin A for 30 minutes, NIH/3T3 cells treated with 100nM Calyculin A for 30 minutes.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

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北方及西南经销商负责:

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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