TU22050

货号 规格 价格(¥)
TU22050S 50ul
TU22050M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

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   免疫荧光

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   植物BPP法变性蛋白提取

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经典一抗-Phospho-Chk1 (S317) Antibody

Datasheet

Background

Checkpoint kinases (Chks) are protein kinases that are involved in cell cycle control. Two checkpoint kinase subtypes have been identified, Chk1 and Chk2. Chk1 is a central component of genome surveillance pathways and is a key regulator of the cell cycle and cell survival. Chk1 is required for the initiation of DNA damage checkpoints and has recently been shown to play a role in the normal (unperturbed) cell cycle. Chk1 impacts various stages of the cell cycle including the S phase, G2/M transition and M phaase. In addition to mediating cell cycle checkpoints, Chk1 also contributes to DNA repair processes, gene transcription, egg production, embryo development, cellular responses to HIV infection and somatic cell viability.

Alternative Name

C85740 antibody
Cell cycle checkpoint kinase antibody
Checkpoint , S. pombe, homolog of, 1 antibody
Checkpoint kinase 1 antibody
Checkpoint kinase 1 homolog (S. pombe) antibody
CHEK 1 antibody
Chek1 antibody
Chk 1 antibody
Chk1 antibody
CHK1 checkpoint homolog (S. pombe) antibody
CHK1_HUMAN antibody
EC 2.7.11.1 antibody
rad27 antibody
Serine/threonine protein kinase Chk1 antibody
Serine/threonine-protein kinase CHK1 antibody
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) antibody

Reactivity

Human,Mouse,Rat

Application

WB,IHC

Recommended Dilution

WB 1:1000
IHC 1:1000

Application Image

Mol Weight

Predicted band size: 54 kDa

Gene Symbol

CHEK1, CHK1

Uniprot

o14757>swissprot: o14757 human;swissprot: o35280 mouse;swissprot: q91zn7 rat

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Recombinant Rabbit monoclonal Antibody

Isotype

IgG

Specificity

Subcellular location

Nucleus, Chromosome, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Research Area

Cancer->Cell cycle;Epigenetics and Nuclear Signaling->DNA / RNA

Positive control

HeLa cell lysate, HeLa treated with UV for 1 hour cell lysate, C6 cell lysate, C6 treated with 100nM Calyculin A for 30 minutes cell lysate, HeLa cells treated with or without UV for 40 minutes, NIH/3T3 cell lysate, NIH/3T3 treated with UV for 40 minutes add 1mM Sodium orthovanadate and recovery for 30 minutes cell lysate, L-929 treated with UV for 3 hours cell lysate.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

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技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
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华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
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陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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