Giantin or Golgin subfamily B member 1 is a protein that in humans is encoded by the GOLGB1 gene. Giantin is located at the cis-medial rims of the Golgi apparatus and is part of the Golgi matrix that is responsible for membrane trafficking in secretory pathway of proteins. This function is key for proper localisation of proteins at the plasma membrane and outside the cell (extracellular region) which is important for cell function that is dependent on for example receptors and the extracellular matrix function. Recent animal model knockout studies of GOLGB1 in mice, rat, and zebrafish have shown that phenotypes are different between species ranging from mild to severe craniofacial defects in the rodent models to just minor size defects in zebrafish. However, in adult zebrafish a tumoral calcinosis-like phenotype was observed, and in humans such phenotype has been linked to defective glycosyltransferase function (e.g. GALNT3 protein).

372 kDa Golgi complex associated protein antibody
372 kDa Golgi complex-associated protein antibody
GCP antibody
GCP372 antibody
Giantin antibody
GOGB1_HUMAN antibody
GOLGB1 antibody
Golgi autoantigen golgin subfamily a member 1 antibody
Golgi autoantigen golgin subfamily b macrogolgin (with transmembrane signal) 1 antibody
Golgi autoantigen, golgin subfamily b, macrogolgin 1 antibody
Golgi complex associated protein 372kDa antibody
Golgi complex-associated protein 372kDa antibody
Golgin B1 antibody
Golgin B1, golgi integral membrane protein antibody
Golgin subfamily B member 1 antibody
GOLIM1 antibody
Macrogolgin antibody
MGC33154 antibody

Human,Mouse,Rat,Monkey

WB,IHC,IF,ICC,FC

WB 1:1000
IHC 1:1000
IF 1:100-1:400
ICC 1:100
FC 1:1000

Predicted band size: 376 kDa

GOLGB1

q14789>swissprot: q14789 human;entrez gene: 192243 rat

Rabbit

Recombinant Rabbit monoclonal Antibody

IgG

Golgi apparatus membrane.

Metabolism->lipid and Glucose metabolism;Organelle Markers->Golgi markers

A549 cell lysate, HeLa cell lysate, Jurkat cell lysate, HepG2 cell lysate, Vero cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse lung tissue lysate, mouse small intestine tissue lysate, rat lung tissue lysate, HeLa, human colon tissue, human kidney tissue, mouse kidney tissue, rat kidney tissue.

Protein A affinity purified.

Liquid

1 mg/mL.

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.