TU22120

货号 规格 价格(¥)
TU22120S 50ul
TU22120M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-PKM1 Antibody

Datasheet

Background

Pyruvate kinase isozymes M1/M2 (PKM1/M2), also known as pyruvate kinase muscle isozyme (PKM), pyruvate kinase type K, cytosolic thyroid hormone-binding protein (CTHBP), thyroid hormone-binding protein 1 (THBP1), or opa-interacting protein 3 (OIP3), is an enzyme that in humans is encoded by the PKM2 gene. Two isozymes are encoded by the PKM gene: PKM1 and PKM2. The M-gene consists of 12 exons and 11 introns. PKM1 and PKM2 are different splicing products of the M-gene (exon 9 for PKM1 and exon 10 for PKM2) and solely differ in 23 amino acids within a 56-amino acid stretch (aa 378–434) at their carboxy terminus.

Alternative Name

CTHBP antibody
Cytosolic thyroid hormone-binding protein antibody
KPYM_HUMAN antibody
OIP-3 antibody
Opa-interacting protein 3 antibody
p58 antibody
pkm antibody
PKM1 antibody
PKM2 antibody
Pyruvate kinase 2/3 antibody
Pyruvate kinase muscle isozyme antibody
Pyruvate kinase PKM antibody
THBP1 antibody
Thyroid hormone-binding protein 1 antibody
Tumor M2-PK antibody

Reactivity

Human,Mouse,Rat

Application

WB,IHC,IF,ICC,FC

Recommended Dilution

WB 1:1000
IHC 1:5000-1:30000
IF 1:100-1:400
ICC 1:500
FC 1:1000

Application Image

Mol Weight

Predicted band size: 58 kDa

Gene Symbol

M1-PK, PKM1

Uniprot

p14618-2>swissprot: p14618-2 human;swissprot: p52480 mouse;swissprot: p11980 rat

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Recombinant Rabbit monoclonal Antibody

Isotype

IgG

Specificity

Subcellular location

Cytoplasm, Nucleus.

Research Area

Cancer->Cancer Metabolism;Cancer->Cancer Metabolism->Metabolic signaling pathway->Metabolism of carbohydrates;Cancer->Cancer Biomarker;Cancer->Cancer Biomarker->Enzymes->MMPs;Signal Transduction->Metabolism;Signal Transduction->Metabolism->Energy Metabolism;Signal Transduction->Metabolism->Mitochondrial;Epigenetics and Nuclear Signaling->Cell cycle;Epigenetics and Nuclear Signaling->Cell cycle->Kinases/Phosphatases->Other;Metabolism->glutamate metabolism;Metabolism->lipid and Glucose metabolism;Metabolism->Cancer Metabolism

Positive control

HCT 116 cell lysate, U-87 MG cell lysate, HeLa cell lysate, human brain tissue lysate, mouse brain tissue lysate, mouse heart tissue lysate, HCT 116, human heart tissue, mouse heart tissue, rat heart tissue.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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