TU22124

货号 规格 价格(¥)
TU22124S 50ul
TU22124M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Phospho-BCAR1 (Y410) Antibody

Datasheet

Background

Breast cancer estrogen resistance protein 1 is a protein that in humans is encoded by the BCAR1 gene. BCAR1 is a ubiquitously expressed adaptor molecule originally identified as the major substrate of v-Src and v-Crk . p130Cas/BCAR1 belongs to the Cas family of adaptor proteins and can act as a docking protein for several signalling partners. Due to its ability to associate with multiple signaling partners, p130Cas/BCAR1 contributes to the regulation to a variety of signaling pathways leading to cell adhesion, migration, invasion, apoptosis, hypoxia and mechanical forces. p130Cas/BCAR1 plays a role in cell transformation and cancer progression and alterations of p130Cas/BCAR1 expression and the resulting activation of selective signalling are determinants for the occurrence of different types of human tumors.

Alternative Name

BCAR 1 antibody
Bcar1 antibody
BCAR1_HUMAN antibody
Breast cancer anti estrogen resistance 1 antibody
Breast cancer anti estrogen resistance 1 protein antibody
Breast cancer estrogen resistance protein 1 antibody
CAS antibody
Cas scaffolding protein family member 1 antibody
CAS1 antibody
Cass1 antibody
Crk associated substrate antibody
Crk associated substrate p130Cas antibody
CRK-associated substrate antibody
CRKAS antibody
FLJ12176 antibody
FLJ45059 antibody
p130cas antibody

Reactivity

Human

Application

WB

Recommended Dilution

WB 1:1000

Application Image

Mol Weight

Predicted band size: 93 kDa

Gene Symbol

BCAR1, CAS, CASS1, CRKAS

Uniprot

p56945>swissprot: p56945 human

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Recombinant Rabbit monoclonal Antibody

Isotype

IgG

Specificity

Subcellular location

Cell junction, focal adhesion, Cytoplasm, Cell projection, axon.

Research Area

Cancer->Signal transduction;Signal Transduction->Protein Phosphorylation

Positive control

HeLa cell lysate, HeLa treated with 1mM sodium orthovanadate for 30 minutes cell lysate.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

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技术支持:15618194176(微信同号)

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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