TU22125

货号 规格 价格(¥)
TU22125S 50ul
TU22125M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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   植物BPP法变性蛋白提取

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经典一抗-Phospho-Nucleophosmin (T199) Antibody

Datasheet

Background

Nucleophosmin (NPM), also known as nucleolar phosphoprotein B23 or numatrin, is a protein that in humans is encoded by the NPM1 gene. NPM1 is associated with nucleolar ribonucleoprotein structures and binds single-stranded and double-stranded nucleic acids, but it binds preferentially G-quadruplex forming nucleic acids. It is involved in the biogenesis of ribosomes and may assist small basic proteins in their transport to the nucleolus. Its regulation through SUMOylation (by SENP3 and SENP5) is another facet of the protein's regulation and cellular functions. It is located in the nucleolus, but it can be translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs.

Alternative Name

B23 antibody
MGC104254 antibody
NO38 antibody
NPM antibody
NPM_HUMAN antibody
NPM1 antibody
Nucleolar phosphoprotein B23 antibody
Nucleolar protein NO38 antibody
Nucleophosmin (nucleolar phosphoprotein B23 numatrin) antibody
Nucleophosmin antibody
nucleophosmin nucleoplasmin family member 1 antibody
Nucleophosmin/nucleoplasmin family member 1 antibody
Numatrin antibody
OTTHUMP00000161024 antibody
OTTHUMP00000161025 antibody
OTTHUMP00000223397 antibody
OTTHUMP00000223398 antibody

Reactivity

Human

Application

WB

Recommended Dilution

WB 1:2000-1:5000

Application Image

Mol Weight

Predicted band size: 33 kDa

Gene Symbol

NPM1, NPM

Uniprot

p06748>swissprot: p06748 human

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Recombinant Rabbit monoclonal Antibody

Isotype

IgG

Specificity

Subcellular location

Nucleus, nucleolus, nucleoplasm, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Research Area

Epigenetics and Nuclear Signaling->DNA / RNA;Epigenetics and Nuclear Signaling->ChIP assays;Epigenetics and Nuclear Signaling->ChIP assays->ChIP kits

Positive control

HeLa cell lysate, HeLa treated with 100ng/mL Nocodazole for 17 hours cell lysate.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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