Serine/threonine-protein kinase PAK 4 is an enzyme that in humans is encoded by the PAK4 gene. Serine/threonine-protein kinase PAK 5 is an enzyme that in humans is encoded by the PAK5 gene. Serine/threonine-protein kinase PAK 6 is an enzyme that in humans is encoded by the PAK6 gene. PAK4 is one of six members of the PAK family of serine/threonine kinases which are divided into group I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK6 and PAK5/7). PAK4 localizes in sub-cellular domains of the cytoplasm and nucleus. PAK4 regulates cytoskeleton remodeling, phenotypic signaling and gene expression, and affects directional motility, invasion, metastasis, and growth. Similar to PAK1, PAK4-signaling-dependent cellular functions also regulate both physiologic and disease processes such as cancer, as PAK4 is overexpressed and/or hyperstimulated in human cancer, at-large. The PAK5 enzyme is one of three members of Group II PAK family of serine/threonine kinases, and evolutionary conserved across species. PAK6 belongs to the Group II PAK family members. Like other family members, PAK6 is also evolutionary conserved across species. Phospho-PAK4+PAK5+PAK6 (S474+S560+S602) Antibody detects endogenous levels of PAK4, PAK5 and PAK6 only when phosphorylated at serine 474, 602, or 560, respectively.

KIAA1142 antibody
p21 activated kinase 4 antibody
p21 Cdc42/Rac1-actiated kinase 4 antibody
P21 protein (Cdc42/Rac) activated kinase 4 antibody
p21(CDKN1A) activated kinase 4 antibody
p21-activated kinase 4 antibody
PAK 4 antibody
PAK-4 antibody
Pak4 antibody
PAK4_HUMAN antibody
Protein kinase related to S.cerevisiae STE20 effector for Cdc42Hs antibody
Serine threonine kinase PAK 4 antibody
Serine/threonine protein kinase PAK 4 antibody
Serine/threonine protein kinase PAK4 antibody
Serine/threonine-protein kinase PAK 4 antibody
EC 2.7.11.1 antibody
KIAA1264 antibody
MGC26232 antibody
p21 activated kinase 7 antibody
p21 protein (Cdc42/Rac)-activated kinase 7 antibody
p21(CDKN1A) activated kinase 7 antibody
p21-activated kinase 5 antibody
p21-activated kinase 7 antibody
PAK 5 antibody
PAK 7 antibody
PAK-5 antibody
PAK-7 antibody
PAK5 antibody
PAK7 antibody
PAK7_HUMAN antibody
Protein kinase PAK5 antibody
Serine/threonine protein kinase PAK 7 antibody
Serine/threonine-protein kinase PAK 7 antibody
CDKN1A activated kinase 6 antibody
EC 2.7.1.37 antibody
p21 activated protein kinase 6 antibody
p21 protein (Cdc42/Rac)-activated kinase 6 antibody
p21(CDKN1A) activated kinase 6 antibody
p21-activated kinase 6 antibody
p21activated kinase 6 antibody
PAK 6 antibody
PAK-6 antibody
Pak6 antibody
PAK6_HUMAN antibody
Serine threonine protein kinase PAK 6 antibody
Serine/threonine protein kinase PAK 6 antibody
Serine/threonine protein kinase PAK6 antibody
Serine/threonine-protein kinase PAK 6 antibody

Human

WB

WB 1:1000

Predicted band size: 64/81/75 kDa

PAK4, KIAA1142, PAK5, KIAA1264, PAK7, PAK6

o96013>swissprot: o96013 human;swissprot: q9p286 human;swissprot: q9nqu5 human

Rabbit

Recombinant Rabbit monoclonal Antibody

IgG

Cytoplasm; Mitochondrion, Cytoplasm, Nucleus; Cytoplasm, Nucleus.

Cell Biology->Cell Cycle;Cell Biology->Cell Cycle->Kinases/Phosphatases->Other;Cell Biology->Apoptosis;Cell Biology->Apoptosis->Intracellular->Kinases;Cancer->Cell cycle;Cancer->Cell cycle->Kinases/phosphatases->Other;Signal Transduction->Cytoskeleton / ECM;Signal Transduction->Protein Phosphorylation;Signal Transduction->Protein Phosphorylation->Ser / Thr Kinases->Other Kinases

A549 cell lysate, HeLa cell lysate, MCF7 cell lysate, HUVEC cell lysate, HUVEC treated with 50ng/mL VEGF for 2 minutes cell lysate.

Protein A affinity purified.

Liquid

1 mg/mL.

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.