TU22247

货号 规格 价格(¥)
TU22247S 50ul
TU22247M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-ICOS Antibody

Datasheet

Background

Inducible T-cell costimulator (also called CD278) is an immune checkpoint protein that in humans is encoded by the ICOS (Inducible T-cell COStimulator) gene. The protein belongs to the CD28 and CTLA-4 cell-surface receptor family. These are proteins expressed on the surface of immune cells that mediate signalling between them. A surface protein, the ligand, binds specifically to its receptor on another cell, leading to a signalling cascade in that cell. ICOS is a receptor protein expressed on the surface of activated T cells. Its ligand ICOS-L (previously called B7RP-1) is constitutively expressed on B cells. Stimulation of the ICOS receptor on T cells by ICOS-L on B cells is required for the development of follicular helper T (Tfh) cells. ICOS forms homodimers and plays an important role in cell-cell signaling, immune responses and regulation of cell proliferation.

Alternative Name

Activation inducible lymphocyte immunomediatory molecule antibody
Activation-inducible lymphocyte immunomediatory molecule antibody
AILIM antibody
CD278 antibody
CD278 antigen antibody
CD28-related Protein-1 antibody
CRP1 antibody
CVID1 antibody
ICOS antibody
ICOS_HUMAN antibody
Inducible costimulator antibody
Inducible T cell co stimulator antibody
Inducible T-cell costimulator antibody
MGC39850 antibody

Reactivity

Mouse,Rat

Application

WB

Recommended Dilution

WB 1:1000

Application Image

Mol Weight

Predicted band size: 23 kDa

Gene Symbol

ICOS, AILIM

Uniprot

q9wvs0>swissprot: q9wvs0 mouse;swissprot: q9r1t7 rat

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Recombinant Rabbit monoclonal Antibody

Isotype

IgG

Specificity

Subcellular location

Cell membrane; Secreted.

Research Area

Positive control

Mouse spleen tissue lysate, mouse thymus tissue lysate, mouse colon tissue lysate, rat spleen tissue lysate, rat thymus tissue lysate.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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