Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins. The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex. The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER. Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC61 channel, contributing to the maintenance of cellular calcium homeostasis. Plays a critical role in nephrogenesis, specifically at pronephros stage.
chunp6898 antibody
fb62c11 antibody
HSEC61 antibody
protein transport protein SEC61 alpha subunit antibody
protein transport protein Sec61 subunit alpha antibody
Protein transport protein Sec61 subunit alpha isoform 1 antibody
S61A1_HUMAN antibody
SEC 61 antibody
SEC 61A antibody
Sec61 alpha 1 antibody
Sec61 alpha 1 subunit antibody
Sec61 alpha 1 subunit (S. cerevisiae) antibody
Sec61 alpha-1 antibody
SEC61 antibody
Sec61 homolog antibody
SEC61A1 antibody
sec61aa antibody
Human,Mouse,Rat
WB,IHC
WB 1:1000IHC 1:200
Predicted band size: 52 kDa
Protein transport protein Sec61 subunit alpha isoform 1
Sec61 alpha-1
SEC61A1
SEC61A
p61619>swissprot: p61619 human;swissprot: p61620 mouse;swissprot: p61621 rat
Rabbit
Recombinant Rabbit monoclonal Antibody
IgG
Endoplasmic reticulum membrane.
Signal Transduction->Protein Trafficking->ER Proteins
HeLa cell lysate, A431 cell lysate, U-87 MG cell lysate, NIH/3T3 cell lysate, C6 cell lysate, human spleen tissue, human kidney tissue, mouse kidney tissue, rat kidney tissue.
Protein A affinity purified.
Liquid
1 mg/mL.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
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应聘职位:hr@ab-mart.com
订购专线:4006-123-828
销售电话:13916964679(微信同号)
技术支持:15618194176(微信同号)
华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:
陆经理:手机13122837132(微信同号)
北方及西南经销商负责:
张经理:手机13122150513(微信同号)

微信客服
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