13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. Recognizes the substrate consensus sequence [ST]-Q. Plays a central role in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating UPF1/RENT1. Recruited by release factors to stalled ribosomes together with SMG8 and SMG9 (forming the SMG1C protein kinase complex), and UPF1 to form the transient SURF (SMG1-UPF1-eRF1-eRF3) complex. In EJC-dependent NMD, the SURF complex associates with the exon junction complex (EJC) through UPF2 and allows the formation of an UPF1-UPF2-UPF3 surveillance complex which is believed to activate NMD. Also acts as a genotoxic stress-activated protein kinase that displays some functional overlap with ATM. Can phosphorylate p53/TP53 and is required for optimal p53/TP53 activation after cellular exposure to genotoxic stress. Its depletion leads to spontaneous DNA damage and increased sensitivity to ionizing radiation (IR). May activate PRKCI but not PRKCZ.
61E3.4 antibody
ATX antibody
hSMG-1 antibody
hSMG1 antibody
KIAA0421 antibody
Lambda interacting protein antibody
Lambda-interacting protein antibody
Lambda/iota protein kinase C interacting protein antibody
Lambda/iota protein kinase C-interacting protein antibody
LIP antibody
Phosphatidylinositol 3 kinase related kinase antibody
Phosphatidylinositol 3 kinase related protein kinase antibody
PI 3 kinase related kinase SMG 1 antibody
Serine/threonine protein kinase SMG1 antibody
Serine/threonine-protein kinase SMG1 antibody
SMG-1 antibody
smg1 antibody
SMG1_HUMAN antibody
Human,Mouse,Rat
WB
WB 1:1000
Predicted band size: 410 kDa
Serine/threonine-protein kinase SMG1
SMG-1; hSMG-1
Lambda/iota protein kinase C-interacting protein
Nonsense mediated mRNA decay-associated PI3K-related kinase SMG1
SMG1
ATX
KIAA0421
LIP
q96q15>swissprot: q96q15 human;swissprot: q8bkx6 mouse;entrez gene: 691397 rat
Rabbit
Recombinant Rabbit monoclonal Antibody
IgG
Cytoplasm. Nucleus.
Epigenetics and Nuclear Signaling->RNAi->miRNA processing
HEK-293 cell lysate, MCF7 cell lysate, C2C12 cell lysate, C6 cell lysate, COS-1 cell lysate.
Protein A affinity purified.
Liquid
1 mg/mL.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
艾比玛特医药科技（上海）有限公司
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南方经销商负责：
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北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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