This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability.

inwardly rectifying subfamily J member 6 antibody
BIR1 antibody
G protein activated inward rectifier potassium channel 2 antibody
G protein-activated inward rectifier potassium channel 2 antibody
GIRK-2 antibody
GIRK2 antibody
hiGIRK2 antibody
Inward rectifier K(+) channel Kir3.2 antibody
Inward rectifier potassium channel KIR3.2 antibody
KATP-2 antibody
KATP2 antibody
KCNJ6 antibody
KCNJ6_HUMAN antibody
Kcnj7 antibody
KIR3.2 antibody
KPLBS antibody
Potassium channel antibody
Potassium channel inwardly rectifying subfamily J member 6 antibody
Potassium inwardly rectifying channel subfamily J member 6 antibody
Potassium voltage gated channel subfamily J member 6 antibody

Human,Mouse,Rat,Cynomolgus monkey,Pig

WB,IHC,IF,ICC,IP

WB 1:1000
IHC 1:1000
IF 1:500
ICC 1:100-1:400
IP 1-2μg/sample

Predicted band size: 48 kDa

G protein-activated inward rectifier potassium channel 2
GIRK-2
BIR1
Inward rectifier K(+) channel Kir3.2
KATP-2
Potassium channel, inwardly rectifying subfamily J member 6
KCNJ6
GIRK2, KATP2, KCNJ7

p48051>swissprot: p48051 human;swissprot: p48542 mouse;swissprot: p48550 rat

Rabbit

Recombinant Rabbit monoclonal Antibody

IgG

Membrane.

Neuroscience

Mouse brain tissue lysate, mouse hippocampus tissue lysate, rat brain tissue lysate, rat hippocampus tissue lysate, human cerebellum tissue, mouse cerebellum tissue, rat cerebellum tissue, mouse brain tissue.

Protein A affinity purified.

Liquid

1 mg/mL.

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.