MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38α, p38β and p38γ, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38α, p38β and p38γ are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.

CSAID Binding Protein 1 antibody
CSAID binding protein antibody
CSAID-binding protein antibody
Csaids binding protein antibody
CSBP 1 antibody
CSBP 2 antibody
CSBP antibody
CSBP1 antibody
CSBP2 antibody
CSPB1 antibody
Cytokine suppressive inflammatory drug-binding protein antibody
EXIP antibody
MAP kinase 14 antibody
MAP kinase MXI2 antibody
MAP kinase p38 alpha antibody
MAPK 14 antibody
MAPK14 antibody
MAX interacting protein 2 antibody
MAX-interacting protein 2 antibody
Mitogen Activated Protein Kinase 14 antibody
Mitogen activated protein kinase p38 alpha antibody
Mitogen-activated protein kinase 14 antibody
Mitogen-activated protein kinase p38 alpha antibody
MK14_HUMAN antibody
Mxi 2 antibody
MXI2 antibody
p38 ALPHA antibody
p38 antibody
p38 MAP kinase antibody
p38 MAPK antibody
p38 mitogen activated protein kinase antibody
p38ALPHA antibody
p38alpha Exip antibody
PRKM14 antibody
PRKM15 antibody
RK antibody
SAPK2A antibody
Stress-activated protein kinase 2a antibody

Human,Mouse,Rat

WB,IHC,IF,ICC,FC

WB 1:2000
IHC 1:500
IF 1:100-1:400
ICC 1:100
FC 1:20000

Predicted band size: 41 kDa

MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A

q16539>swissprot: q16539 human;swissprot: p47811 mouse;swissprot: p70618 rat

Rabbit

Recombinant Rabbit monoclonal Antibody

IgG

Cytoplasm, Nucleus.

Signal Transduction

Jurkat cell lysate, Jurkat treated with UV for 1 hour cell lysate, NIH/3T3 treated with 25μg/mL Anisomycin for 30 minutes cell lysate, C6 treated with 25μg/mL Anisomycin for 30 minutes cell lysate, mouse colon tissue, rat colon tissue, NIH/3T3 cells treated with 25μg/mL Anisomycin for 30 minutes.

Protein A affinity purified.

Liquid

1 mg/mL.

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.