TU22765

货号 规格 价格(¥)
TU22765S 50ul
TU22765M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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经典一抗-Phospho-Met (Y1234/Y1235) Antibody

Datasheet

Background

Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. HGF receptor is a single pass tyrosine kinase receptor essential for embryonic development, organogenesis and wound healing. Hepatocyte growth factor/Scatter Factor (HGF/SF) and its splicing isoform (NK1, NK2) are the only known ligands of the HGF receptor. MET is normally expressed by cells of epithelial origin, while expression of HGF/SF is restricted to cells of mesenchymal origin. When HGF/SF binds its cognate receptor MET it induces its dimerization through a not yet completely understood mechanism leading to its activation.

Alternative Name

AUTS9 antibody
c met antibody
D249 antibody
Hepatocyte growth factor receptor antibody
HGF receptor antibody
HGF/SF receptor antibody
HGFR antibody
MET antibody
Met proto oncogene antibody
Met proto oncogene tyrosine kinase antibody
MET proto oncogene, receptor tyrosine kinase antibody
Met proto-oncogene (hepatocyte growth factor receptor) antibody
Met proto-oncogene antibody
Met protooncogene antibody
MET_HUMAN antibody
Oncogene MET antibody
Par4 antibody
Proto-oncogene c-Met antibody
RCCP2 antibody
Scatter factor receptor antibody
SF receptor antibody
Tyrosine-protein kinase Met antibody

Reactivity

Human

Application

WB

Recommended Dilution

WB 1:1000

Application Image

Mol Weight

Predicted band size: 156 kDa

Gene Symbol

Hepatocyte growth factor receptor
HGF receptor
HGF/SF receptor
Proto-oncogene c-Met
Scatter factor receptor (SF receptor)
Tyrosine-protein kinase Met
MET

Uniprot

p08581>swissprot: p08581 human

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Recombinant Rabbit monoclonal Antibody

Isotype

IgG

Specificity

Subcellular location

Membrane; Secreted.

Research Area

Signal Transduction->Protein Phosphorylation->Tyrosine Kinases->Receptor Tyrosine Kinases;Epigenetics and Nuclear Signaling->Transcription->Cancer susceptibility->Proto-oncogenes

Positive control

HeLa cell lysate, HeLa starved for 16 hours then treated with 20ng/mL HGF for 10 minutes cell lysate.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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