This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq].

YES1(phospho Y426); c Yes; c-Yes; Cellular Yes 1 protein; Cellular Yes1 protein; HsT441; P61 YES; p61-Yes; Proto oncogene tyrosine protein kinase YES; Proto-oncogene c-Yes; Proto-oncogene tyrosine-protein kinase Yes; v yes 1 Yamaguchi sarcoma viral oncogene homolog 1; Viral oncogene yes 1 homolog 1; Viral oncogene yes1 homolog 1; Yamaguchi sarcoma oncogene; Yes 1; Yes; YES_HUMAN; YES1.

Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,GuineaPig

WB

WB 1:500-2000

60kD

7525

P07947

https://www.uniprot.org/uniprotkb/P07947

Cell membrane. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytosol. Note=Newly synthesized protein initially accumulates in the Golgi region and traffics to the plasma membrane through the exocytic pathway.

Expressed in the epithelial cells of renal proximal tubules and stomach as well as hematopoietic cells in the bone marrow and spleen in the fetal tissues. In adult, expressed in epithelial cells of the renal proximal tubules and present in keratinocytes in the basal epidermal layer of epidermis.

KLH conjugated Synthesised phosphopeptide derived from human YES1 around the phosphorylation site of Tyr426

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.