TD13219

货号 规格 价格(¥)
TD13219S 50μl
TD13219M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-SC35 Antibody

Datasheet

Background

Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. Can bind to beta-globin mRNA and commit it to the splicing pathway. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment.

Alternative Name

Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2) SRSF2 SFRS2

Reactivity

Human, Mouse, Rat

Predicted Reactivity

Pig, Bovine, Dog, Chicken, Xenopus

Application

WB,IHC,IF,ICC

Application Image

Recommended Dilution

WB 1:500-1:2000
IHC 1:50-1:500
IF 1:50-1:500
ICC 1:50-1:500

Mol Weight

25kD; 25kDa(Calculated).

Gene Symbol

SRSF2 SFRS2

Uniprot

q01130

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Polyclonal

Isotype

Rabbit IgG

Specificity

SC35 Antibody detects endogenous levels of total SC35.

Subcellular location

Nucleus localization

Research Area

mRNA processing #mRNA splicing

Positive control

Conjugation

Modification

Purification

Formulation

Concentration

Buffer

PBS,pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

产品介绍

Clone

Target

波长

Storage

Store at -20 °C. Stable for 12 months from date of receipt.

注意事项

Companion Products

Important

Comments

RRID

客户评价

艾比玛特医药科技(上海)有限公司
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技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
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南方经销商负责:

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

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