Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Microtubule-actin crosslinking factor 1 (MACF1/ACF7) belongs to spectraplakin family of proteins which also includes mammalian Bpag1/dystonin, Drosophila Short Stop (Shot) and Caenorhabditis elegans Vab-10. These are large actin-microtubule linker molecules that are essential for various biological processes such as neuronal degeneration, wound healing, gastrulation. MACF1, located on mouse chromosome 4D2.2, was found to play an important role during neurogenesis- it was shown that MACF1 regulates the organization of neuronal microtubules which is essential for axon extension. Furthermore, MACF1 is required in controlling focal adhesion assembly and dynamics. MACF1 behaves as an actin-regulated ATPase and it has the ability to target microtubules that track along F-actin to focal adhesions. MACF1 was also implicated in regulating filopodia formation.
ABP620;
Acf7;
Aclp7;
Actin cross linking family 7;
MACF;
Microtubule actin crosslinking factor 1;
mKIAA0465;
R74989;
rabeculin alpha.
Human,Mouse,Rat,Chicken,Cow,Sheep
IHC,IF,ICC
IHC 1:100-500IF 1:100-500ICC 1:100-1:400
839kD
23499
Q9QXZ0
Cytoplasmic, microtubule. Plasma membrane. Golgi apparatus.
KLH conjugated synthetic peptide derived from human MACF1/ACF7
Rabbit
Polyclonal
IgG
affinity purified by Protein A
Liquid
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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订购专线:4006-123-828
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华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
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徐经理:手机15618191473(微信同号)
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