Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq].
myosin light chain kinase; DKFZp686I10125; EC 2.7.11.18; FLJ12216; Kinase related protein; KRP; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; MYLK1; Myosin light chain kinase smooth muscle and non muscle isozymes; Myosin light polypeptide kinase; OTTHUMP00000180642; OTTHUMP00000180643; smMLCK; Smooth muscle myosin light chain kinase; Telokin; deglutamylated form; MLCK; MYLK_HUMAN.
Human,Rat,Mouse,Chicken,Dog,Pig,Cow,Horse,Sheep,GuineaPig
IHC,IF,ICC,FC
IHC 1:50-1:200IF 1:100-500ICC 1:100-1:400FC 1:100
210kD
4638
Q15746
Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific. Non-muscle isoform 2 is the dominant splice variant expressed in various tissues. Telokin has been found in a wide variety of adult and fetal tissues.
KLH conjugated synthetic peptide derived from human MLCK
Rabbit
Polyclonal
affinity purified by Protein A
Liquid
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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订购专线:4006-123-828
销售电话:13916964679(微信同号)
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华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
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徐经理:手机15618191473(微信同号)
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陆经理:手机13122837132(微信同号)
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张经理:手机13122150513(微信同号)

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