Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
PLEKHA7 (pleckstrin homology domain containing, family A member 7), also known as PH domain-containing family A member 7, is a 1,121 amino acid protein that contains one PH domain and two WW domains. Encoded by a gene that maps to human chromosome 11p15.1, PLEKHA7 exists as three alternatively spliced isoforms. Localizing to cell-cell junctions in Caco2 cells, PLEKHA7 interacts with the adherens junction protein p120 in human colon carcinoma cells. PLEKHA7 also colocalizes with zona adherens proteins and is necessary for zonula adherens biogenesis and maintenance. Associated with systolic blood pressure (SBP) and hypertension, PLEKHA7 is a potential target for the prevention or treatment of hypertension. PLEKHA7 is also linked to autoimmune hepatitis type 1, a chronic active hepatitis characterized by hypergammaglobulinemia and autoantibodies.
DKFZp686M22243;
PH domain-containing family A member 7;
PKHA7_HUMAN;
Pleckstrin homology domain containing family A member 2;
Pleckstrin homology domain-containing family A member 7;
Plekha7.
Human
WB,IHC,IF,ICC
WB 1:500-2000IHC 1:100-500IF 1:100-1:400ICC 1:100-1:400
127kD
144100
Q6IQ23
Cell junction > adherens junction. Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Localizes to zonula adherens, recruited via its interaction with CTNND1.
KLH conjugated synthetic peptide derived from human PLEKHA7
Rabbit
Polyclonal
affinity purified by Protein A
Liquid
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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订购专线:4006-123-828
销售电话:13916964679(微信同号)
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华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
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徐经理:手机15618191473(微信同号)
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