PC14504

货号 规格 价格(¥)
PC14504S 50ul
PC14504M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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经典一抗-phospho-EDG1 (Thr236) Rabbit pAb

Datasheet

Background

Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 is a G-protein-coupled receptor which binds the bioactive signaling molecule sphingosine 1-phosphate (S1P). S1PR1 belongs to a sphingosine-1-phosphate receptor subfamily comprising five members (S1PR1-5). S1PR1 was originally identified as an abundant transcript in endothelial cells and it has an important role in regulating endothelial cell cytoskeletal structure, migration, capillary-like network formation and vascular maturation. In addition, S1PR1 signaling is important in the regulation of lymphocyte maturation, migration and trafficking.

Alternative Names

EDG1 (phospho T236); p-EDG1 (phospho T236);
CD363;
CHEDG 1;
CHEDG1;
D1S3362;
ECGF 1;
ECGF1;
EDG 1;
EDG1;
endothelial differentiation G protein coupled receptor 1;
Endothelial differentiation G-protein coupled receptor 1;
Endothelial differentiation sphingolipid G protein coupled receptor 1;
FLJ58121;
G protein coupled sphingolipid receptor;
g protein-coupled receptor edg-1;
S1P receptor 1;
S1P receptor Edg 1;
S1P receptor Edg-1;
S1P receptor Edg1;
S1P(1) receptor;
S1P1;
s1pr1;
S1PR1_HUMAN;
sphingolipid g-protein-coupled receptor 1;
Sphingosine 1 phosphate receptor Edg 1;
Sphingosine 1 phosphate receptor EDG1;
sphingosine 1- phosphate receptor 1;
Sphingosine 1-phosphate receptor 1;
Sphingosine 1-phosphate receptor Edg-1;
Sphingosine 1phosphate receptor type 1 S1P1.

Reactivity

Mouse,Rat,Human,Pig,Rabbit

Application

WB

Recommended Dilution

WB 1:500-2000

Application Image

Mol Weight

43kD

Gene ID

1901

UniProt

P21453

Uniprot link

Subcellular location

Cell membrane; Multi-pass membrane protein.

Specificity

Endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin.

Immunogen

KLH conjugated synthesised phosphopeptide derived from human EDG1 around the phosphorylation site of Thr236

Source

Rabbit

Clonality

Polyclonal

Isotype

IgG

Purification

affinity purified by Protein A

Formulation

Liquid

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Concentrate

Storage Condition

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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