PC5776

货号 规格 价格(¥)
PC5776S 50ul
PC5776M 100ul

以上产品均有现货供应

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-PDGF-D/SCDGFB Rabbit pAb

Datasheet

Background

SCDGFB (Spinal cord derived growth factor B) is a member of the platelet derived growth factor family. It only forms homodimers and does not dimerize with the other three family members. It is a potent mitogen for cells of mesenchymal origin. It is activated by proteolytic cleavage and this active form acts as a specific ligand for beta platelet derived growth factor receptor. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. It induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis.

Alternative Names

IEGF; Iris expressed growth factor; Iris-expressed growth factor; MGC26867; MSTP036; PDGF D; PDGF-D; PDGFD; PDGFD latent form; PDGFD receptor-binding form; PDGFD_HUMAN; Platelet derived growth factor D; Platelet-derived growth factor D; receptor-binding form; SCDGF B; SCDGF-B; Spinal cord derived growth factor B; Spinal cord-derived growth factor B.

Reactivity

Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep

Application

WB

Recommended Dilution

WB 1:500-2000

Application Image

Mol Weight

14/41kD

Gene ID

80310

UniProt

Q9GZP0

Uniprot link

Subcellular location

Secreted. Note=Released by platelets upon wounding.

Specificity

Expressed at high levels in the heart, pancreas, adrenal gland and ovary and at low levels in placenta, liver, kidney, prostate, testis, small intestine, spleen and colon. In the kidney, expressed by the visceral epithelial cells of the glomeruli. A widespread expression is also seen in the medial smooth muscle cells of arteries and arterioles, as well as in smooth muscle cells of vasa rectae in the medullary area. Expressed in the adventitial connective tissue surrounding the suprarenal artery. In chronic obstructive nephropathy, a persistent expression is seen in glomerular visceral epithelial cells and vascular smooth muscle cells, as well as de novo expression by periglomerular interstitial cells and by some neointimal cells of atherosclerotic vessels. Expression in normal prostate is seen preferentially in the mesenchyme of the gland while expression is increased and more profuse in prostate carcinoma. Expressed in many ovarian, lung, renal and brain cancer-derived cell lines.

Immunogen

KLH conjugated synthetic peptide derived from human SCDGFB

Source

Rabbit

Clonality

Polyclonal

Isotype

IgG

Purification

affinity purified by Protein A

Formulation

Liquid

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Concentrate

Storage Condition

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

艾比玛特医药科技(上海)有限公司
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应聘职位:hr@ab-mart.com

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技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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