TFII I is a ubiquitously expressed multifunctional transcription factor with broad biological roles in transcription and signal transduction in a variety of cell types. It has been shown that TFII I can interact physically and functionally with Btk (Bruton's tyrosine kinase), a hematopoietic non-receptor protein tyrosine kinase that is critical for B lymphocyte development.

BAP135 (phospho Y248); p-BAP135 (phospho Y248); TFII I (phospho Y248); p-TFII I (phospho Y248);
BAP 135;
BAP-135;
BAP135;
Bruton tyrosine kinase associated protein 135;
Bruton tyrosine kinase-associated protein 135;
BTK associated protein 135;
BTK associated protein 135kD;
BTK associated protein;
BTK-associated protein 135;
BTKAP 1;
BTKAP1;
DIWS;
FLJ38776;
FLJ56355;
General transcription factor II i;
General transcription factor II-I;
General transcription factor IIi;
GTF 2I;
GTF2I;
GTF2I_HUMAN;
GTFII I;
GTFII-I;
IB 291;
IB291;
SPIN;
SRF Phox 1 interacting protein;
SRF Phox1 interacting protein;
SRF-Phox1-interacting protein;
TFII-I;
Transcription factor II I;
WBS;
WBSCR 6;
WBSCR6;
Williams Beuren syndrome chromosome region 6;
Williams Beuren syndrome chromosome region 6 protein;
Williams-Beuren syndrome chromosomal region 6 protein

Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep

WB

WB 1:500-2000

112kD

2968

P78347

https://www.uniprot.org/uniprotkb/P78347

Cytoplasm. Nucleus. Colocalizes with BTK in the cytoplasm.

Ubiquitous. Isoform 1 is strongly expressed in fetal brain, weakly in adult brain, muscle, and lymphoblasts and is almost undetectable in other adult tissues, while the other isoforms are equally expressed in all adult tissues.

KLH conjugated synthesised phosphopeptide derived from human TFII I around the phosphorylation site of Tyr248

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.