Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified. [provided by RefSeq, Jul 2008]

Collagen/fibrinogen domain containing lectin 3 p35;
Collagen/fibrinogen domain containing protein 3;
FCN 3;
FCNH;
Ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen);
Ficolin (collagen/fibrinogen domain containing) 3;
Ficolin 3;
H ficolin;
HAKA1;
Hakata antigen;
MGC22543.

Human

WB

WB 1:500-2000

30kD

8547

O75636

https://www.uniprot.org/uniprotkb/O75636

Secreted. Note: Found in blood plasma, bronchus, alveolus and bile duct.

Liver and lung. In liver it is produced by bile duct epithelial cells and hepatocytes. In lung it is produced by both ciliated bronchial epithelial cells and type II alveolar epithelial cells.

KLH conjugated synthetic peptide derived from human FCN3

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.