The Fc receptor homolog (FcRH) family of proteins are related to the classical Fc receptors (FcR) and belong to the immunoglobulin receptor superfamily. The proteins in the FcRH family are type I transmembrane glycoproteins and consist of FcRH1-FcRH6. The genes encoding the human FcRH proteins map to chromosome 1, near the related FCR genes. The FcRH proteins, which are involved in immune system regulation, have immunoreceptor-tyrosine inhibitory motifs in their cytoplasmic domains. Mutations in the gene encoding for the FcRH proteins may be associated with systemic lupus erythematosus, autoimmune thyroid disease and rheumatoid arthritis. The FcRH genes are expressed primarily, although not exclusively, by mature B lineage cells, and may serve important regulatory roles in normal and neoplastic B cell development.

CD307b;
Fc receptor homolog 2;
Fc receptor like protein 2;
Fc receptor-like protein 2;
FcR-like protein 2;
FcRH2;
FCRL 2;
FcRL2;
FCRL2_HUMAN;
IFGP family protein 4;
IFGP4;
Immunoglobulin receptor translocation associated 4 protein;
Immunoglobulin receptor translocation-associated protein 4;
IRTA4;
SH2 domain containing phosphatase anchor protein 1;
SH2 domain-containing phosphatase anchor protein 1;
SPAP1.

Mouse,Human

WB

WB 1:500-2000

53kD

79368

Q96LA5

https://www.uniprot.org/uniprotkb/Q96LA5

Cell membrane.

Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B-cell lines. Preferentially expressed in memory B-cells (at protein level).

KLH conjugated synthetic peptide derived from human FcRH2

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.