Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.
Basic helix loop helix domain containing class B protein 7; Bhlhb7; bHLHe20; Class B basic helix loop helix protein 7; Class B basic helix-loop-helix protein 7; Class E basic helix loop helix protein 20; Class E basic helix-loop-helix protein 20; Olig3; OLIG3_HUMAN; Oligo3; Oligodendrocyte specific bHLH transcription factor 3; Oligodendrocyte transcription factor 3.
Mouse,Human,Rat
WB
WB 1:500-2000
29kD
167826
Q7RTU3
Nucleus.
KLH conjugated synthetic peptide derived from human OLIG3
Rabbit
Polyclonal
affinity purified by Protein A
Liquid
Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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