The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Localized to the intermembrane space, COX6b2 (Cytochrome c oxidase subunit 6B2), also known as Cytochrome c oxidase subunit VIb isoform 2 and Cancer/testis antigen 59, is a 88 amino acid mitochondrial protein that is responsible for joining the two COX monomers to form the COX dimer. COX6b2 is specifically expressed in testis and is found to be upregulated in certain cancer cell lines.

Cancer/testis antigen 59; COX VIb-2; Cox6b2; COXVIb-2; COXVIb2; CT59; CX6B2_HUMAN; Cytochrome c oxidase subunit 6B2; Cytochrome c oxidase subunit VIb; Cytochrome c oxidase subunit VIb isoform 2; cytochrome c oxidase subunit VIb polypeptide 2 (testis); Cytochrome c oxidase subunit VIb testes specific; Cytochrome c oxidase subunit VIb, testis-specific isoform; FLJ46422; MGC119094; testis-specific isoform.

Human,Mouse,Rat,Cow,Sheep

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

11kD

125965

Q6YFQ2

https://www.uniprot.org/uniprotkb/Q6YFQ2

Mitochondrion intermembrane space.

Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines.

KLH conjugated synthetic peptide derived from human COX6B2

Rabbit

Polyclonal

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.