The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle and non-muscle-specific isoforms. COX8 exists as three isoforms: COX8a, a liver and heart isoform, Cox8b, a heart-specific isoform, and Cox8c, whose expression pattern has yet to be elucidated. All three Cox8 isoforms exists as components of the COX complex and play an important role in electron transport.

COX VIII-3; COX8-3; Cox8c; COX8C_HUMAN; cytochrome c oxidase polypeptide 8; Cytochrome c oxidase polypeptide 8 isoform 3; cytochrome c oxidase polypeptide VIII; Cytochrome c oxidase polypeptide VIII isoform 3; Cytochrome c oxidase subunit 8-3; Cytochrome c oxidase subunit 8C; Cytochrome c oxidase subunit 8C, mitochondrial; cytochrome c oxidase subunit VIII; cytochrome c oxidase subunit VIIIC; mitochondrial.

Human

IF,ICC,ELISA

IF 1:100-500
ICC 1:100-1:400
ELISA 1:5000-10000

4.8kD

341947

Q7Z4L0

https://www.uniprot.org/uniprotkb/Q7Z4L0

Mitochondrion inner membrane.

It is not yet known where COX8C is expressed.

KLH conjugated synthetic peptide derived from human COX8C

Rabbit

Polyclonal

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.