This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols. [provided by RefSeq, Jul 2008]

GNT1;
UGT1A7;
OTTHUMP00000065199;
UD17_HUMAN;
UDP glucuronosyltransferase 1A7;
UDP glucuronosyltransferase;
UDP glycosyltransferase 1 family polypeptide A7;
UDP-glucuronosyltransferase 1 family polypeptide A7s;
UDP-glucuronosyltransferase 1-7;
UDP-glucuronosyltransferase 1-G;
UDP-glucuronosyltransferase 1A7;
UDP>
UDPGT 1-7;
UGT-1G;
UGT1;
UGT1*7;
UGT1-07;
UGT1.7;
UGT1A7;
UGT1G.

Mouse,Rat,Pig

WB,IHC,IF,ICC

WB 1:500-2000
IHC 1:100-500
IF 1:100-1:400
ICC 1:100-1:400

57kD

54577

Q9HAW7

https://www.uniprot.org/uniprotkb/Q9HAW7

Microsome. Endoplasmic reticulum membrane.

Liver and gastric tissue.

KLH conjugated synthetic peptide derived from rat UGT1A7

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.