Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The KIAA1797 gene product has been provisionally designated KIAA1797 pending further characterization.

FOCAD;
FOCAD_HUMAN;
Focadhesin;
KIAA1797.

Human,Mouse,Rat,Dog,Pig

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

200kD

54914

Q5VW36

https://www.uniprot.org/uniprotkb/Q5VW36

Membrane. Cell junction; focal adhesion. Colocalizes with VCL in astrocytes.

Ubiquitous. High expression in brain followed by testis, muscle, pancreas, heart, ovary, small intestine, placenta, prostate, thymus, kidney, colon, liver, lung, spleen and leukocytes. Expression is reduced in most glioblastomas and all glioblastoma cell lines.

KLH conjugated synthetic peptide derived from human Focadhesin

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.