Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The high-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription (1–5). HMG-14 and HMG-17 also function as architectural elements, which alter the structure of the chromatin fiber and enhance transcription from chromatin templates (1–3,5). HMG-14/17 proteins modify the nucleosomal organization of the 30 nm chromatin fiber and mediate the unfolding of the higher order chromatin structure thereby facilitating access to the underlying DNA sequence (1–3). Clustering of architectural elements, such as HMG proteins and linker histone subtypes into distinct domains, may lead to structural and functional heterogeneity along the chromatin fiber (1–3). In addition, HMG-14 and HMG-17 have been identified as constitutive components of mouse oocyte and embryonic chromatin that establish a link between the structure of embryonic chromatin and the normal progression of embryonic development (2).
High mobility group (nonhistone chromosomal) protein 17;
high mobility group nucleosomal binding domain 2;
High mobility group nucleosome-binding domain-containing protein 2;
High mobility group protein N2;
HMG17;
HMGN2;
HMGN2_HUMAN;
MGC5629;
Non histone chromosomal protein HMG 17;
Non-histone chromosomal protein HMG-17;
Nonhistone chromosomal protein HMG 17;
nonhistone chromosomal protein hmg-17.
Mouse,Rat,Human,Dog,Pig,Cow,Sheep
IHC,IF,ICC
IHC 1:100-500IF 1:100-500ICC 1:100-1:400
9.2kD
3151
P05204
Nucleus. Cytoplasm. Cytoplasmic enrichment upon phosphorylation.
KLH conjugated synthetic peptide derived from human HMGN2/HMG17
Rabbit
Polyclonal
IgG
affinity purified by Protein A
Liquid
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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