This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq].

CK 13;
CK 14;
CK 15;
CK 16;
CK13;
CK14;
CK15;
CK16;
Cytokeratin 13;
Cytokeratin 14;
Cytokeratin 15;
Cytokeratin 16;
EBS3;
EBS4;
K13;
K14;
K15;
K16;
K1CO;
K1CP;
Keratin 13;
Keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner);
Keratin 14;
Keratin 15;
Keratin 15, basic;
Keratin 15, beta;
Keratin 16 (focal non epidermolytic palmoplantar keratoderma);
Keratin 16;
Keratin, type I cytoskeletal 13;
Keratin, type I cytoskeletal 16;
KRT13;
KRT14;
KRT15;
KRT16;
KRT16A;
KRTB;
NEPPK;
NFJ;
Type I cytoskeletal 15.

Human,Mouse,Rat,Dog,Horse

WB

WB 1:500-2000

51kD

3861

P08779

https://www.uniprot.org/uniprotkb/P08779

Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern.

Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.

KLH conjugated synthetic peptide derived from human HMW Cytokeratin

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.