PC9971

货号 规格 价格(¥)
PC9971S 50ul
PC9971M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-CREPT Rabbit pAb

Datasheet

Background

Interacts with phosphorylated C-terminal heptapeptide
repeat domain (CTD) of the largest RNA polymerase II subunit
POLR2A, and participates in dephosphorylation of the CTD.
Transcriptional regulator which enhances expression of CCND1.
Promotes binding of RNA polymerase II to the CCDN1 promoter and to
the termination region before the poly-A site but decreases its
binding after the poly-A site. Prevents RNA polymerase II from
reading through the 3' end termination site and may allow it to be
recruited back to the promoter through promotion of the formation
of a chromatin loop. Also enhances the transcription of a number of
other cell cycle-related genes including CDK2, CDK4, CDK6 and
cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.

Alternative Names

C20orf77; Cell cycle related and expression elevated protein in tumor; Chromosome 20 open reading frame 77; CREPT; dJ1057B20.2; DKFZp434P0735; FLJ44520; Hypothetical protein LOC58490; Uncharacterized protein C20orf77; RPR1B_HUMAN.

Reactivity

Mouse,Human,Rat,Chicken

Application

WB

Recommended Dilution

WB 1:500-2000

Application Image

Mol Weight

37kD

Gene ID

58490

UniProt

Q9NQG5

Uniprot link

Subcellular location

Nucleus.

Specificity

Preferentially expressed in a range of tumor tissues including colon, lung, liver, breast, prostate, stomach, uterine endometrium and cervical cancers with higher levels in tumors than in adjacent non-tumor tissue (at protein level).

Immunogen

KLH conjugated synthetic peptide derived from human CREPT

Source

Rabbit

Clonality

Polyclonal

Isotype

IgG

Purification

affinity purified by Protein A

Formulation

Liquid

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Concentrate

Storage Condition

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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